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AB-FUBICA

AB-FUBICA (Compound 13) is a CB1 and CB2 receptor agonist that activates G-protein coupled inwardly rectifying potassium channels (GIRK) by binding to CB1 and CB2 receptors, displaying notable cannabinoid-like activity. AB-FUBICA has EC50 values of 21 nM for CB1 and 15 nM for CB2. AB-FUBICA may be suitable for studying pain management, neurodegenerative diseases, and inflammation-related mechanisms[1].

Product Specifications

CAS Number

1801338-22-6

UNSPSC

12352005

Target

Cannabinoid Receptor; Potassium Channel

Type

Reference compound

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ab-fubica.html

Smiles

CC(C)[C@@H](C(N)=O)NC(C1=CN(CC2=CC=C(C=C2)F)C3=CC=CC=C13)=O

Molecular Formula

C21H22FN3O2

Molecular Weight

367.42

References & Citations

[1]Banister SD, et al. Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA. ACS Chem Neurosci. 2015 Sep 16;6 (9) :1546-59.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CB1; CB2

Available Sizes

Frequently Asked Questions

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