Senkyunolide A
Senkyunolide A is a phthalide, anti-tumor cell proliferation agent with anticancer activity. Senkyunolide A protects neurons from corticosterone -induced apoptosis by decreasing protein phosphatase PP2A and α-synuclein phosphorylation and protein level. Senkyunolide A also inhibits osteoarthritis through the NLRP3 signaling pathway and suppresses the expression of CD137, a diagnostic biomarker for atherosclerosis[1][2][3][4][5].
Product Specifications
CAS Number
63038-10-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
α-synuclein
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/senkyunolide-a.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1O[C@@H](CCCC)C2=C1C=CCC2
Molecular Formula
C12H16O2
Molecular Weight
192.26
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light, stored under nitrogen
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
α-synuclein
Available Sizes
Frequently Asked Questions
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