Aam-KTX
Aam-KTX is a Kv channel inhibitor with IC50 values of 1.1 nM and >750 nM for Kv1.3 and Kv1.1, respectively. Aam-KTX is a toxic peptide obtained from the venom of the scorpion Mesobuthus eupeus. Aam-KTX has potential in autoimmune diseases research[1].
Product Specifications
UNSPSC
12352209
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aam-ktx.html
Solubility
10 mM in DMSO
Smiles
O=C(CN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]2CCCCN)=O)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CCSC)=O)=O)C)=O)CC(O)=O)=O)CCCCN)=O)CSSC[C@H](NC4=O)C(N[C@H](C(N5[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CCC5)=O)[C@@H](C)O)=O)=O)CCC1)=O)CCCCN)=O)[C@H](CC)C)=O)CSSC[C@H](NC6=O)C(N[C@H]4CC7=CNC=N7)=O)=O)CCC(N)=O)=O)CC8=CNC=N8)=O)CO)=O)=O)[C@@H](C)O)=O)CSSCC(NC2=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]6CCCCN)=O)CCCNC(N)=N)=O)CC(N)=O)=O)[C@H](CC)C)=O)=O)CCCCN)=O)C(C)C)=O)CC(N)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)C(C)C
Molecular Formula
C174H288N58O48S7
Molecular Weight
4184.96
References & Citations
[1]Zhu S, et al. Molecular diversity and functional evolution of scorpion potassium channel toxins. Mol Cell Proteomics. 2011 Feb;10 (2) :M110.002832.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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