Neutral protease, Paenibacillus polymyxa

Neutral protease, Paenibacillus polymyxa (Dispase II, Dispase) is a neutral protease and potent fibronectinase and type IV collagenase. Neutral protease, Paenibacillus polymyxa can be used to separate the intact epidermis from the dermis and intact epithelial sheets in culture from the substratum[1][2].

Product Specifications

CAS Number

[42613-33-2]

Product Name Alternative

Dispase II, Dispase

UNSPSC

12352204

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/neutral-protease-paenibacillus-polymyxa.html

Solubility

H2O : 25 mg/mL (ultrasonic)

Smiles

[Neutralprotease,Paenibacilluspolymyxa]

Precautions

H302, H315, H319, H335

References & Citations

[1]Stenn KS, et al. Dispase, a neutral protease from Bacillus polymyxa, is a powerful fibronectinase and type IV collagenase. J Invest Dermatol. 1989 Aug;93 (2) :287-90. |[2]Calvo B, et al. Dissociation of neonatal and adult mice brain for simultaneous analysis of microglia, astrocytes and infiltrating lymphocytes by flow cytometry. IBRO Rep. 2020 Jan 13;8:36-47.