N3-PEG4-C2-NH2
N3-PEG4-C2-NH2 (PROTAC Linker 20) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. N3-PEG4-C2-NH2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[951671-92-4]
Product Name Alternative
PROTAC Linker 20
UNSPSC
12352211
Hazard Statement
H314
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-linker-20.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NCCOCCOCCOCCOCCN=[N+]=[N-]
Molecular Formula
C10H22N4O4
Molecular Weight
262.31
Precautions
H314
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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