Mefluleucine
Mefluleucine (NV-5138), a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. Mefluleucine is used for antidepressant studies[1][2].
Product Specifications
Product Name Alternative
NV-5138
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
MTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nv-5138.html
Purity
98.0
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
N[C@@H](CC(C)(C(F)F)C)C(O)=O
Molecular Formula
C7H13F2NO2
Molecular Weight
181.18
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114384/NV-5138-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114384/Mefluleucine-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 2
Citation 01
CAS Number
[2095886-80-7]
Available Sizes
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