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6,7-Dichloroquinoline-5,8-dione

6,7-Dichloroquinoline-5,8-dione (compound DA3002) is a potent CDC25B2 inhibitor with an IC50 value of 4.6 µM. 6,7-Dichloroquinoline-5,8-dione has the potential for the research of cancer[1].

Product Specifications

CAS Number

6541-19-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-7-dichloroquinoline-5-8-dione.html

Purity

98.26

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C1=CN=C2C(=C1)C(=O)C(=C(C2=O)Cl)Cl

Molecular Formula

C9H3Cl2NO2

Molecular Weight

228.03

Precautions

H302, H315, H319, H335

References & Citations

[1]Lazo JS, et al. Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25. J Med Chem. 2001 Nov 22;44 (24) :4042-9.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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