6,7-Dichloroquinoline-5,8-dione
6,7-Dichloroquinoline-5,8-dione (compound DA3002) is a potent CDC25B2 inhibitor with an IC50 value of 4.6 µM. 6,7-Dichloroquinoline-5,8-dione has the potential for the research of cancer[1].
Product Specifications
CAS Number
[6541-19-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-7-dichloroquinoline-5-8-dione.html
Purity
98.26
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C1=CN=C2C(=C1)C(=O)C(=C(C2=O)Cl)Cl
Molecular Formula
C9H3Cl2NO2
Molecular Weight
228.03
Precautions
H302, H315, H319, H335
References & Citations
[1]Lazo JS, et al. Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25. J Med Chem. 2001 Nov 22;44 (24) :4042-9.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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