Ragifilimab

Ragifilimab (INCAGN-1876) is an agonist monoclonal antibody targeting the glucocorticoid-induced TNFR-related protein (GITR) . Ragifilimab binds to and activates GITR on T cells, which stimulates the immune system to enhance its anti-tumor activity. Ragifilimab can be used for advanced or metastatic solid tumors research[1].

Product Specifications

CAS Number

[2207590-51-8]

Product Name Alternative

INCAGN-1876

UNSPSC

12352203

Target

TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ragifilimab.html

Purity

99.32

Solubility

H2O

Smiles

[Ragifilimab]

Molecular Weight

(146.46 kDa)

References & Citations

[1]Hernandez-Guerrero T, et al: Not Ready for Prime Time. Clin Cancer Res. 2022 Sep 15;28 (18) :3905-3907.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Isoform

TNFRSF18/GITR/CD357

Available Sizes

Curated Selection

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