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PROTAC BET-binding moiety 2

PROTAC BET-binding moiety 2 is an inhibitor of BET bromodomain[1].

Product Specifications

CAS Number

[916493-82-8]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/PROTAC_BET-binding_moiety_2.html

Purity

99.77

Solubility

DMSO : 42.86 mg/mL (ultrasonic)

Smiles

CC1=C(C(O)=O)SC2=C1C(C3=CC=C(Cl)C=C3)=N[C@@H](CC(OC)=O)C4=NN=C(C)N24

Molecular Formula

C20H17ClN4O4S

Molecular Weight

444.89

Precautions

H315, H319, H335

References & Citations

[1]James E. Bradner, et al. Bivalent bromodomain inhibtors and uses thereof. WO2017091673A2.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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