Glycine-15N

Glycine-15N is the 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[1].

Product Specifications

CAS Number

[7299-33-4]

UNSPSC

12352211

Target

Endogenous Metabolite; iGluR

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/glycine-15n.html

Purity

99.84

Solubility

H2O : 23.33 mg/mL (ultrasonic)

Smiles

[15NH2]CC(O)=O

Molecular Formula

C2H5 15NO2

Molecular Weight

76.06

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Johnson JW, et al. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987 Feb 5-11;325 (6104) :529-31.