Enzalutamide-d6
Enzalutamide-d6 (MDV3100-d6) is a deuterium labeled Enzalutamide (MDV3100) . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells[1].
Product Specifications
CAS Number
[1443331-94-9]
Product Name Alternative
MDV3100-d6
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Androgen Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.85
Solubility
10 mM in DMSO|DMF : ≥ 25mg/mL|DMSO : ≥ 20mg/mL|Ethanol : ≥ 0.5mg/mL
Smiles
O=C(NC)C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3)=S)C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C2=O)C=C1F
Molecular Formula
C21H10D6F4N4O2S
Molecular Weight
470.47
Precautions
H315, H319, H335
References & Citations
[1]Tran C, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009 May 8;324 (5928) :787-90.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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