Autocamtide-2-related inhibitory peptide (TFA)

Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.

Product Specifications

UNSPSC

12352209

Target

Autophagy; CaMK

Type

Peptides

Related Pathways

Autophagy; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Autocamtide-2-related_inhibitory_peptide_TFA.html

Purity

99.20

Solubility

H2O : 110 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N.OC(C(F)(F)F)=O

Molecular Formula

C66H126N22O21F3

Molecular Weight

1611.76

References & Citations

[1]Ishida A, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212 (3) :806-12.