Isocitric acid

Isocitric acid is an endogenous metabolite present in Saliva and Cellular_Cytoplasm that can be used for the research of Alzheimer's Disease, Lewy Body Dementia and Anoxia[1][2][3].

Product Specifications

CAS Number

[320-77-4]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Isocitric_acid.html

Purity

99.14

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

OC(C(O)=O)C(C(O)=O)CC(O)=O

Molecular Formula

C6H8O7

Molecular Weight

192.12

Precautions

H315, H319, H335

References & Citations

[1]Tsuruoka M, et al. Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurodegenerative dementia patients. Electrophoresis. 2013 Oct;34 (19) :2865-72.|[2]Zupke C, et al. Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas. Appl Microbiol Biotechnol. 1995 Dec;44 (1-2) :27-36.|[3]Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39 (35) :5709-5720.