PROTAC erf3a Degrader-1
PROTAC erf3a Degrader-1 (Compound C63) is an orally active PROTAC erf3a Degrader. PROTAC erf3a Degrader-1 inhibits cancer cell proliferation (eg: 22Rv1) . PROTAC erf3a Degrader-1 can be used for research of prostate cancer, ovarian cancer, liver cancer, cervical cancer, leukemia, breast cancer. (Red: erf3a ligand (HY-13778) ; Black: linker (HY-163960) ; Blue: CRBN ligand (HY-41547) ) [1].
Product Specifications
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-erf3a-degrader-1.html
Purity
99.44
Solubility
DMSO : 60 mg/mL (ultrasonic)
Smiles
Molecular Formula
C44H52N6O6
Molecular Weight
760.92
References & Citations
[1]Guangliang Yu, et al. Medicine for treating human tumor by eRF3a targeting protein degradation mechanism. Patent. CN117801051A.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163938/PROTAC-erf3a-Degrader-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163938/PROTAC-erf3a-Degrader-1-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[3033871-19-8]
Available Sizes
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