Polyphyllin II
Product Specifications
CAS Number
76296-72-5
UNSPSC Description
Polyphyllin II is one of the most significant saponins in Rhizoma Paridis and has toxic effects on kinds of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell-cycle arrest[1].
Target Antigen
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/polyphyllin-ii.html
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC[C@H]([C@@H](O[C@@H]1O[C@@H](CO)[C@H](O)[C@H]1O)C(O[C@H]2[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O2)[C@H]3O)O[C@H]3O[C@H](C4)CC[C@@]5(C)C4=CC[C@]6([H])[C@]5([H])CC[C@@]7(C)[C@@]6([H])C[C@@]8([H])[C@]7([H])[C@H](C)[C@]9(OC[C@H](C)CC9)O8
Molecular Weight
855.02
References & Citations
[1]Wang W, et al. Apoptosis in HepaRG and HL-7702 cells inducted by polyphyllin II through caspases activation and cell-cycle arrest. J Cell Physiol. 2019 May;234(5):7078-7089.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Clinical Information
No Development Reported
Available Sizes
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