2-Acetonaphthone

2-Acetonaphthone is a synthetic fragrance material. 2-Acetonaphthone increases ROS under UVA/sunlight, leading to endoplasmic reticulum stress and decreased mitochondrial membrane potential. 2-Acetonaphthone can be used as an adulterant in a variety of cosmetics. 2-Acetonaphthone can be used for the study of skin keratinization[1]

Product Specifications

CAS Number

[93-08-3]

UNSPSC

12352005

Hazard Statement

H411

Target

Mitochondrial Metabolism; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/2-acetonaphthone.html

Concentration

10mM

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=CC=C2C=CC=CC2=C1)=O

Molecular Formula

C12H10O

Molecular Weight

170.21

Precautions

H411

References & Citations

[1]Chandra S, et al. Involvement of Type-I and Type-II Photodynamic Reactions in Photosensitization of Fragrance Ingredient 2-acetonaphthone. Photochem Photobiol. 2022 Sep;98 (5) :1050-1058.