Thyrotropin-Releasing Hormone (TRH), Free Acid
Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) is a physiological metabolite of Thyrotropin-Releasing Hormone.
Product Specifications
CAS Number
[24769-58-2]
Product Name Alternative
TRH-OH
UNSPSC
12352209
Target
TSH Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Thyrotropin-Releasing_Hormone__TRH_,_Free_Acid.html
Purity
99.44
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O)[C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H](CC3)NC3=O)=O)=O)CCC1
Molecular Formula
C16H21N5O5
Molecular Weight
363.37
References & Citations
[1]Kagabu Y, et al. Effects of thyrotropin-releasing hormone and its metabolites, Cyclo (His-Pro) and TRH-OH, on growth hormone and prolactin synthesis in primary cultured pituitary cells of the common carp, Cyprinus carpio. Gen Comp Endocrinol. 1998 Sep;111 (3) :395-403.|[2]López-Barneo J, et al. Thyrotropin-releasing-hormone (TRH) and its physiological metabolite TRH-OH inhibit Na+ channel activity in mammalian septal neurons. Proc Natl Acad Sci U S A. 1990 Oct;87 (20) :8150-4.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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