c-Fms-IN-10
Product Specifications
UNSPSC Description
c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, an kinase inhibitor of FMS (Colony stimulating factor-1 receptor, CSF-1R) with IC50 of 2 nM.
c-Fms-IN-10 has anti-tumor activity[1].
Target Antigen
c-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c-fms-in-10.html
Purity
98.63
Solubility
DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
NC1=NC=NC2=C1SC=C2C(NC3=C(C(C)=NN4CC5=CC=CC(C)=N5)C4=CC=C3)=O
Molecular Weight
429.50
References & Citations
[1]Kim YY， et al. Synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel FMS inhibitors. Bioorg Med Chem Lett. 2019 Jan 15;29(2):271-275.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126297/c-Fms-IN-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126297/c-Fms-IN-10-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1527517-50-5
Available Sizes
Curated Selection
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