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ZL006

ZL006 is a potent inhibitor of nNOS/PSD-95 interaction, and inhibits NMDA receptor-mediated NO synthesis.

Product Specifications

CAS Number

1181226-02-7

UNSPSC

12352005

Hazard Statement

H315-H319

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ZL006.html

Concentration

10mM

Purity

99.23

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

O=C(O)C1=CC=C(NCC2=CC(Cl)=CC(Cl)=C2O)C=C1O

Molecular Formula

C14H11Cl2NO4

Molecular Weight

328.15

Precautions

P264-P280-P302+P352-P305+P351+P338-P362+P364

References & Citations

[1]Wang Z, et al. Enhanced anti-ischemic stroke of ZL006 by T7-conjugated PEGylated liposomes drug delivery system. Sci Rep. 2015 Jul 29;5:12651.|[2]Bach A, et al. Biochemical investigations of the mechanism of action of small molecules ZL006 and IC87201 as potential inhibitors of the nNOS-PDZ/PSD-95-PDZ interactions. Sci Rep. 2015 Jul 16;5:12157.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NMDA Receptor

Available Sizes

Frequently Asked Questions

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