L-162313

L-162313 is a non-peptide angiotensin II AT1 and AT2 receptor agonist, with IC50 values of 1.1 and 2.0 nM for AT1 and AT2 receptor, respectively. L-162313 can be used for the research of vasoconstriction, aldosterone release, and cardiovascular growth[1].

Product Specifications

CAS Number

[151488-11-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-162313.html

Purity

98.51

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NS(=O)(C1=C(C2=CC=C(CN3C4=NC(C)=CC(C)=C4N=C3CC)C=C2)C=C(CC(C)C)S1)=O)OCCCC

Molecular Formula

C30H38N4O4S2

Molecular Weight

582.78

Precautions

H302, H315, H319

References & Citations

[1]Wan Y, et al. First reported nonpeptide AT1 receptor agonist (L-162,313) acts as an AT2 receptor agonist in vivo. J Med Chem. 2004 Mar 11;47 (6) :1536-46.