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Dynapyrazole-A

Dynapyrazole A is a specific inhibitor of microtubule dynamin that specifically inhibits the ATPase activity of microtubule-stimulated dynamin without blocking microtubule-independent basal activity[1].

Product Specifications

CAS Number

[2226517-75-3]

UNSPSC

12352005

Target

Dynamin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dynapyrazole-a.html

Purity

98.17

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N#CC1=C(N2)N(N=C1C3(C4=CC=C(Cl)C=C4)CC3)C5=C(C=C(I)C=C5)C2=O

Molecular Formula

C20H12ClIN4O

Molecular Weight

486.69

References & Citations

[1]Zhaoyang Jing, et al. Rotavirus Viroplasm Biogenesis Involves Microtubule-Based Dynein Transport Mediated by an Interaction between NSP2 and Dynein Intermediate Chain. J Virol. 2021 Oct 13;95 (21) :e0124621.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-131873/Dynapyrazole-A-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-131873/Dynapyrazole-A-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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