Des-Leu10-angiotensin I
Product Specifications
UNSPSC Description
Des-Leu10-angiotensin I is a nonapeptide that inhibits rabbit lung angiotensin-converting enzyme peptidyl-dipeptide hydrolase with a Ki value of 31 μM, which is generated from angiotensin I by the action of carboxypeptidase-like activities residing in the human platelet and mast cell[1].
Target Antigen
Drug Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/des-leu10-angiotensin-i.html
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@H](C(O)=O)CC4=CN=CN4)=O)CC5=CC=CC=C5)=O)=O)=O)=O
Molecular Weight
1183.32
References & Citations
[1]Snyder RA, et al. Inhibition of angiotensin-converting enzyme by des-Leu10-angiotensin I: a potential mechanism of endogenous angiotensin-converting enzyme regulation. Biochim Biophys Acta. 1986 May 12;871(1):1-5.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3006/Des-Leu10-angiotensin-I-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3006/
Clinical Information
No Development Reported
CAS Number
34273-12-6
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