HDAC10-IN-2 (hydrochloride)
HDAC10-IN-2 hydrochloride (compound 10c) is a potent and highly selective HDAC10 inhibitor, with an IC50 of 20 nM. HDAC10-IN-2 hydrochloride modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells[1].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; HDAC
Type
Reference compound
Related Pathways
Autophagy; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac10-in-2-hydrochloride.html
Purity
96.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NO)/C=C/C1CCN(CC1)CC2=CC=CC3=C2C=CC=C3.[H]Cl
Molecular Formula
C19H23ClN2O2
Molecular Weight
346.85
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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