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MNK2 Rabbit Polyclonal Antibody

MAP kinase-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MKNK2 gene. MNK2 has been shown to interact with MAPK1 and Eukaryotic translation initiation factor 4 gamma. MNK2 has been identified as a therapeutic target for diabetes. Specifically, blocking MNK2 interaction with eIF4G has been shown to boost protein synthesis and promote beta cell regeneration.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

G protein coupled receptor kinase 7 antibody GPRK7 antibody MAP kinase interacting serine threonine kinase 2 antibody MAP kinase interacting serine threonine kinase antibody MAP kinase interacting serine threonine protein kinase 2 antibody MAP kinase signal integrating kinase 2 antibody MAP kinase signal-integrating kinase 2 antibody MAP kinase-interacting serine/threonine-protein kinase 2 antibody MAPK interacting kinase 2 antibody MAPK signal integrating kinase 2 antibody Mitogen activated protein kinase interacting serine threonine kinase 2 antibody Mknk2 antibody MKNK2_HUMAN antibody Mnk2 antibody Putative map kinase interacting kinase antibody

Abbreviation

MKNK2, GPRK7, MNK2

Swiss Prot

Q9HBH9 Human, Q8CDB0 Mouse, Q5U2N4 Rat

Cellular Locus

Nucleus, PML body; Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human MNK2 aa 266-465 / 465.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

Jurkat cell lysate, HeLa cell lysate, SK-OV-3 cell lysate, HepG2 cell lysate, rat ovary tissue lysate, mouse testis tissue, rat skeletal muscle tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:1,000-1:2,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 52 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

Frequently Asked Questions

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