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GPR35 agonist 4

Product Specifications

UNSPSC Description

GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].

Target Antigen

GPR35

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/gpr35-agonist-4.html

Purity

99.0

Solubility

DMSO : 27.9 mg/mL (ultrasonic)

Smiles

O=C(NC(S/1)=O)C1=C\C2=CC=C(C=C2)OCC(O)=O

Molecular Weight

279.27

References & Citations

[1]Jenkins L, et al. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2. Br J Pharmacol. 2011 Feb;162(3):733-48.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-107539/GPR35-agonist-4-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-107539/GPR35-agonist-4-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

871085-49-3

Available Sizes

Curated Selection

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