GPR35 agonist 4
GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].
Product Specifications
CAS Number
[871085-49-3]
UNSPSC
12352005
Target
GPR35
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gpr35-agonist-4.html
Purity
99.0
Solubility
DMSO : 27.9 mg/mL (ultrasonic)
Smiles
O=C(NC(S/1)=O)C1=C\C2=CC=C(C=C2)OCC(O)=O
Molecular Formula
C12H9NO5S
Molecular Weight
279.27
References & Citations
[1]Jenkins L, et al. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2. Br J Pharmacol. 2011 Feb;162 (3) :733-48.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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