MO-I-1100
MO-I-1100 is an inhibitor of ASPH (Aspartyl- (Asparaginyl) -β-hydroxylase) enzymatic activity. MO-I-1100 suppresses HCC cell migration, invasion and anchorage independent growth. MO-I-1100 shows antitumor effects through inhibiting Notch signaling cascade in HCC[1].
Product Specifications
CAS Number
1585217-40-8
UNSPSC
12352005
Target
Notch
Type
Reference compound
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mo-i-1100.html
Purity
99.76
Solubility
DMSO : 15 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C(OS(CC2=CC=CC=C2)(=O)=O)=C(N)OC1C3=CC=C(Cl)C=C3
Molecular Formula
C17H14ClNO5S
Molecular Weight
379.81
References & Citations
[1]Aihara A, et al. A cell-surface β-hydroxylase is a biomarker and therapeutic target for hepatocellular carcinoma. Hepatology. 2014 Oct;60 (4) :1302-13.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
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Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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