MO-I-1100

MO-I-1100 is an inhibitor of ASPH (Aspartyl- (Asparaginyl) -β-hydroxylase) enzymatic activity. MO-I-1100 suppresses HCC cell migration, invasion and anchorage independent growth. MO-I-1100 shows antitumor effects through inhibiting Notch signaling cascade in HCC[1].

Product Specifications

CAS Number

[1585217-40-8]

UNSPSC

12352005

Target

Notch

Type

Reference compound

Related Pathways

Neuronal Signaling; Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mo-i-1100.html

Purity

99.76

Solubility

DMSO : 15 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C(OS(CC2=CC=CC=C2)(=O)=O)=C(N)OC1C3=CC=C(Cl)C=C3

Molecular Formula

C17H14ClNO5S

Molecular Weight

379.81

References & Citations

[1]Aihara A, et al. A cell-surface β-hydroxylase is a biomarker and therapeutic target for hepatocellular carcinoma. Hepatology. 2014 Oct;60 (4) :1302-13.