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Biotin-PEG3-aldehyde

Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[889443-90-7]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/biotin-peg3-aldehyde.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=C1N[C@H]2[C@H](CS[C@H]2CCCCC(NCCOCCOCCOCCNC(C3=CC=C(C([H])=O)C=C3)=O)=O)N1

Molecular Formula

C26H38N4O7S

Molecular Weight

550.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker

Available Sizes

Curated Selection

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