ZM226600
ZM226600 is an ATP-sensitive potassium channel opener (EC50: 500 nM) . ZM226600 inhibits bladder spontaneous activity[1][2].
Product Specifications
CAS Number
[147695-92-9]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/zm226600.html
Concentration
10mM
Purity
99.95
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(S(=O)(C2=CC=CC=C2)=O)C=C1)C(C)(O)C(F)(F)F
Molecular Formula
C16H14F3NO4S
Molecular Weight
373.35
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Pinna C, et al. Effect of the ATP-sensitive potassium channel opener ZM226600 on cystometric parameters in rats with ligature-intact, partial urethral obstruction. Eur J Pharmacol. 2005 May 23;516 (1) :71-7. |[2]Grant TL, et al. Anilide tertiary carbinols: a novel series of K+ channel openers. Trends Pharmacol Sci. 1994 Nov;15 (11) :402-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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