GLP-1 (32-36) amide
GLP-1 (32-36) amide, a pentapeptide, derived from the C terminus of the glucoregulatory hormone GLP-1. GLP-1 (32-36) amide could inhibit weight gain and modulate whole body glucose metabolism in diabetic mice[1][2].
Product Specifications
CAS Number
1417302-71-6
UNSPSC
12352209
Target
GCGR
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/glp-1-32-36-amide.html
Purity
98.44
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
N=C(N)NCCC[C@@H](C(N)=O)NC(CNC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](CC(C)C)N)=O)=O)=O)=O
Molecular Formula
C25H50N10O5
Molecular Weight
570.73
References & Citations
[1]Elahi D, et, al. GLP-1 (32-36) amide, a novel pentapeptide cleavage product of GLP-1, modulates whole body glucose metabolism in dogs. Peptides. 2014 Sep;59:20-4.|[2]Sun L, et, al. Novel Pentapeptide GLP-1 (32-36) Amide Inhibits β-Cell Apoptosis In Vitro and Improves Glucose Disposal in Streptozotocin-Induced Diabetic Mice. Chem Biol Drug Des. 2015 Dec;86 (6) :1482-90.|[3]Tomas E, et, al. GLP-1 (32-36) amide Pentapeptide Increases Basal Energy Expenditure and Inhibits Weight Gain in Obese Mice. Diabetes. 2015 Jul;64 (7) :2409-19.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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