Rabbit Anti-Human PKD1L2 Polyclonal Antibody [AF488]

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by slow progression of multiple renal cysts, leading to middle-age or late-stage renal insufficiency. ADPKD is mainly related to mutations in the PKD1 gene (encoding polycystin-1 or PC1). PKD1L2 (polycystic kidney disease gene 1-like 2), as a member of the polycystic protein family, can act as a component of the cation channel pore, which is very impoRoom Temperatureant in the study of ADPKD.