Pseudohypericin (Standard)

Pseudohypericin (Standard) is the analytical standard of Pseudohypericin. This product is intended for research and analytical applications. Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity[1][2].

Product Specifications

CAS Number

[55954-61-5]

UNSPSC

12352005

Target

HIV; Reference Standards

Type

Reference compound

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/pseudohypericin-standard.html

Smiles

O=C1C2=C3C4=C5C1=C(O)C=C(CO)C5=C6C(C)=CC(O)=C7C6=C4C8=C(C(O)=CC(O)=C8C3=C(O)C=C2O)C7=O

Molecular Formula

C30H16O9

Molecular Weight

520.44

References & Citations

[1]Lavie G, et al. Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin. Proc Natl Acad Sci U S A. 1989 Aug;86 (15) :5963-7.|[2]Zheng X, et al. Apoptosis of THP-1 Macrophages Induced by Pseudohypericin-Mediated Sonodynamic Therapy Through the Mitochondria-Caspase Pathway. Cell Physiol Biochem. 2016;38 (2) :545-57.|[3]Lavie G, et al. Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin. Proc Natl Acad Sci U S A. 1989 Aug;86 (15) :5963-7.|[4]Zheng X, et al. Apoptosis of THP-1 Macrophages Induced by Pseudohypericin-Mediated Sonodynamic Therapy Through the Mitochondria-Caspase Pathway. Cell Physiol Biochem. 2016;38 (2) :545-57.