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Hydrazide-PEG4-Desthiobiotin

Hydrazide-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hydrazide-peg4-desthiobiotin.html

Purity

95.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |Methanol : ≥ 125 mg/mL

Smiles

O=C(NCCOCCOCCOCCOCCC(NN)=O)CCCCC[C@H]([C@H](C)N1)NC1=O

Molecular Formula

C21H41N5O7

Molecular Weight

475.58

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Frequently Asked Questions

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