3-Methyl-2-quinoxalinecarboxylic acid-d4
3-Methyl-2-quinoxalinecarboxylic acid-d4 is the deuterium labeled 3-Methyl-2-quinoxalinecarboxylic acid. 3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1].
Product Specifications
CAS Number
[2244217-93-2]
Product Name Alternative
MQCA-d4
UNSPSC
12352005
Hazard Statement
H302, H319, H335
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Cancer
Purity
99.95
Solubility
10 mM in DMSO|DMF : ≥ 25mg/mL|DMSO : ≥ 30mg/mL|Ethanol : ≥ 25mg/mL
Smiles
O=C(C1=NC2=C([2H])C([2H])=C([2H])C([2H])=C2N=C1C)O
Molecular Formula
C10H4D4N2O2
Molecular Weight
192.21
Precautions
H302, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Keyu Zhang , et al. Cytotoxicity and Genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic Acid (MQCA) in Human Hepatocytes. Res Vet Sci. 2012 Dec;93 (3) :1393-401.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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