FTO-IN-3
FTO-IN-3 is a FTO inhibitor that impair self-renewal in glioblastoma stem cells.
Product Specifications
CAS Number
[2585198-87-2]
UNSPSC
12352005
Target
Fat Mass and Obesity-associated Protein (FTO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fto-in-3.html
Purity
99.79
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; adjust pH to 2 with 1M HCl; heat to 80°C)
Smiles
NC1=NC2=CC=C(C3=CN=C(OC)N=C3)C=C2S1
Molecular Formula
C12H10N4OS
Molecular Weight
258.30
References & Citations
[1]Huff S, et al. m6A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells. ACS Chem Biol. 2021 Feb 19;16 (2) :324-333.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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