Lck-IN-3
Lck-IN-3 (compound 7m) is an LCK inhibitor targeting acute lymphoblastic leukemia (ALL) that inhibits LCK phosphorylation. Lck-IN-3 can induce cell cycle arrest in the G2/M phase, leading to apoptosis in ALL cells[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Src
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lck-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(SC(NC(CC2=CC=C(C)C=C2)=O)=N3)=C3C=C1)N4C=CC5=C4C=C(C6=CN(C)N=C6)C=N5
Molecular Formula
C28H22N6O2S
Molecular Weight
506.58
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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