(Rac) -PD 151746
(Rac) -PD 151746 is the optically inactive racemate of PD 151746 (HY-19749) . PD 151746 is a neuroprotective calpain inhibitor with Ki values of 0.26 μM (u-calpain) and 5.33 μM (m-calpain), respectively[1].
Product Specifications
CAS Number
[179461-52-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-pd-151746.html
Smiles
O=C(O)/C(S)=C/C1=CNC2=C1C=C(F)C=C2
Molecular Formula
C11H8FNO2S
Molecular Weight
237.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Wang KK, et al. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective. Proc Natl Acad Sci U S A. 1996 Jun 25;93 (13) :6687-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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