(Rac) -PD 151746

(Rac) -PD 151746 is the optically inactive racemate of PD 151746 (HY-19749) . PD 151746 is a neuroprotective calpain inhibitor with Ki values of 0.26 μM (u-calpain) and 5.33 μM (m-calpain), respectively[1].

Product Specifications

CAS Number

[179461-52-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Proteasome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-pd-151746.html

Smiles

O=C(O)/C(S)=C/C1=CNC2=C1C=C(F)C=C2

Molecular Formula

C11H8FNO2S

Molecular Weight

237.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Wang KK, et al. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective. Proc Natl Acad Sci U S A. 1996 Jun 25;93 (13) :6687-92.