Octreotide (acetate)
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
Product Specifications
CAS Number
79517-01-4
Product Name Alternative
SMS 201-995 (acetate)
UNSPSC
12352209
Hazard Statement
H315, H319
Target
Somatostatin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease; Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/Octreotide-acetate.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)C(N[C@H](CO)[C@H](O)C)=O)NC([C@H](N)CC2=CC=CC=C2)=O)=O)CC3=CC=CC=C3)N[C@@H]1CC4=CNC5=CC=CC=C45.CC(O)=O
Molecular Formula
C51H70N10O12S2
Molecular Weight
1079.29
Precautions
H315, H319
References & Citations
[1]Wang M, et al. Pharmacokinetic and pharmacodynamic study of a phospholipid-based phase separation gel for once a month administration of octreotide. J Control Release. 2016 May 28;230:45-56.|[2]Kim S, et al. Treatment of Gastrin-Secreting Tumor With Sustained-Release Octreotide Acetate in a Dog. J Am Anim Hosp Assoc. 2015 Nov-Dec;51 (6) :407-12.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
Launched
Citation 01
J Biol Chem. 2025 Jul 30;301 (9) :110544.|Mol Med Rep. 2024 Jun;29 (6) :90.|Nat Commun. 2023 Feb 21;14 (1) :962.|Patent. US20240307504A1.|Research Square Print. 2022 Aug.|Basic Clin Pharmacol Toxicol. 2022 Sep;131 (3) :174-188.|Biomacromolecules. 2024 May 13;25 (5) :2749-2761.|Cell Mol Bioeng. 2022 Dec 22;16 (1) :55-67.|Eur J Nucl Med Mol Imaging. 2024 Nov;51 (13) :4099-4110.|Faculty of Biological and Environmental Sciences. University of Helsinki Finland. 2018 Dec.|J Pharm Biomed Anal. 2022 Mar 20:211:114518.|J Pharm Biomed Anal. 2023 Feb 5:224:115156.|J Pharm Sci. 2022 Dec;111 (12) :3417-3423.|Mol Cancer. 2024 Sep 20;23 (1) :205.
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