Robenidine hydrochloride

Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC50s of 8.1 and 4.7 μM, respectively.

Product Specifications

CAS Number

[25875-50-7]

UNSPSC

12352005

Hazard Statement

H302, H372, H410

Target

Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Robenidine_hydrochloride.html

Purity

99.00

Solubility

DMSO : 6.25 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

N=C(N/N=C/C1=CC=C(Cl)C=C1)N/N=C/C2=CC=C(Cl)C=C2.[H]Cl

Molecular Formula

C15H14Cl3N5

Molecular Weight

370.66

Precautions

H302, H372, H410

References & Citations

[1]Abraham RJ, et al. Robenidine Analogues as Gram-Positive Antibacterial Agents. J Med Chem. 2016 Mar 10;59 (5) :2126-38.|[2]Liu C, et al. Influence of three coccidiostats on the pharmacokinetics of florfenicol in rabbits. Exp Anim. 2015;64 (1) :73-9.