PROTAC BRD4 ligand-2 (hydrochloride)
PROTAC BRD4 ligand-2 hydrochloride is a ligand for target BRD4 protein for PROTAC CFT-2718.
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-ligand-2-hydrochloride.html
Purity
99.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(C2=NC3(CC3)C4=NN=C(C)N4C5=CC=C(C6=CNN=C6)C=C25)C=C1.[H]Cl
Molecular Formula
C22H18Cl2N6
Molecular Weight
437.32
References & Citations
[1]Sun D, et al. Evaluation of the Small-molecule BRD4 Degrader CFT-2718 in Small-cell Lung Cancer and Pancreatic Cancer Models. Mol Cancer Ther. 2021 Aug;20 (8) :1367-1377.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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