Tiotidine
Tiotidine (ICI 125211) is a potent and selective antagonist of histamine H2-receptor (pA2=7.3-7.8 for guinea-pig right atrium) . Tiotidine has low affinity for both the H1 and the H3 receptors[1][2].
Product Specifications
CAS Number
[69014-14-8]
Product Name Alternative
ICI 125211
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tiotidine.html
Concentration
10mM
Purity
99.28
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CN/C(NC#N)=N\CCSCC1=CSC(NC(N)=N)=N1
Molecular Formula
C10H16N8S2
Molecular Weight
312.42
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101232/Tiotidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101232/Tiotidine-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H1 Receptor; H2 Receptor; H3 Receptor
Available Sizes
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