Uridine triphosphate (trisodium salt)

Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors[1][2].

Product Specifications

CAS Number

[19817-92-6]

Product Name Alternative

UTP trisodium salt; Uridine 5'-triphosphate trisodium salt

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; P2Y Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/uridine-triphosphate-trisodium-salt.html

Purity

99.05

Solubility

H2O : 75 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(OP(OP([O-])([O-])=O)([O-])=O)(O)=O.[3Na+]

Molecular Formula

C9H12N2Na3O15P3

Molecular Weight

550.09

Precautions

H302, H315, H319, H335

References & Citations

[1]Choi JH, et al. Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor. Pancreas. 2013 May;42 (4) :680-6.|[2] Lamarca A, et al. Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation. PLoS One. 2014 Jun 6;9 (6) :e98998.|[3]Yitzhaki S, et al. Uridine-5'-triphosphate (UTP) reduces infarct size and improves rat heart function aftermyocardial infarct. Biochem Pharmacol. 2006 Oct 16;72 (8) :949-55.