2’-Deoxy-2’-fluoro-b-D-arabinocytidine (hydrochloride)
2’-Deoxy-2’-fluoro-b-D-arabinocytidine (hydrochloride) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Product Specifications
CAS Number
25183-22-6
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-deoxy-2-fluoro-b-d-arabinocytidine-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)[C@H](F)[C@H](N2C=CC(N)=NC2=O)O1.Cl
Molecular Formula
C9H13ClFN3O4
Molecular Weight
281.67
References & Citations
[1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3 (11) :1062-8.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
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