RL-6-Me-7-OH

RL-6-Me-7-OH is a hapten that activates human and mouse MAIT cells (EC50 = 25 µM) . RL-6-Me-7-OH can be combined with carrier proteins and used in antigen design. RL-6-Me-7-OH can be used in inflammation and immunity research[1].

Product Specifications

CAS Number

[2184-54-5]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rl-6-me-7-oh.html

Purity

96.56

Solubility

DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 125 mg/mL (ultrasonic)

Smiles

CC1=C(N(C2=NC(NC(C2=N1)=O)=O)C[C@H](O)[C@@H]([C@H](O)CO)O)O

Molecular Formula

C12H16N4O7

Molecular Weight

328.28

References & Citations

[1]Corbett AJ, et al. Antigen Recognition by MR1-Reactive T Cells; MAIT Cells, Metabolites, and Remaining Mysteries. Front Immunol. 2020 Aug 27;11:1961.