Trimebutine-d5 (fumarate)
Product Specifications
UNSPSC Description
Trimebutine-d5 (fumarate) is deuterium labeled Trimebutine.
Target Antigen
Isotope-Labeled Compounds; Opioid Receptor
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein;Neuronal Signaling;Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
OC(/C=C/C(O)=O)=O.O=C(C1=CC(OC)=C(C(OC)=C1)OC)OCC(C([2H])([2H])C([2H])([2H])[2H])(C2=CC=CC=C2)N(C)C
Molecular Weight
508.57
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Hiyama, T., et al., Effectiveness of prokinetic agents against diseases external to the gastrointestinal tract. J Gastroenterol Hepatol, 2009. 24(4): p. 537-46.|[3]Kaneto, H., M. Takahashi, and J. Watanabe, The opioid receptor selectivity for trimebutine in isolated tissues experiments and receptor binding studies. J Pharmacobiodyn, 1990. 13(7): p. 448-53.|[4]Roman, F.J., et al., Pharmacological properties of trimebutine and N-monodesmethyltrimebutine. J Pharmacol Exp Ther, 1999. 289(3): p. 1391-7.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
2747915-18-8
Available Sizes
Curated Selection
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