Pleconaril

Pleconaril is a picornavirus capsid binding inhibitor that prevents attachment and/or virus uncoating. Pleconaril has potential for use in rhinoviruses and enteroviruses research[1][2].

Product Specifications

CAS Number

[153168-05-9]

Product Name Alternative

VP 63843; Win 63843

UNSPSC

12352005

Hazard Statement

H301, H413

Target

Enterovirus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Pleconaril.html

Purity

99.48

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(C1=NC(C2=CC(C)=C(OCCCC3=CC(C)=NO3)C(C)=C2)=NO1)(F)F

Molecular Formula

C18H18F3N3O3

Molecular Weight

381.35

Precautions

H301, H413

References & Citations

[1]Benschop KS, et al. Genetic and antigenic structural characterization for resistance of echovirus 11 to pleconaril in an immunocompromised patient. J Gen Virol. 2015 Mar;96 (Pt 3) :571-9.|[2]Lee JS, et al. Antiviral Activity of Itraconazole against Echovirus 30 Infection In Vitro. Osong Public Health Res Perspect. 2017 Oct;8 (5) :318-324.|[3]Zhang G, et al. In vitro and in vivo evaluation of ribavirin and pleconaril antiviral activity against enterovirus 71 infection. Arch Virol. 2012 Apr;157 (4) :669-79.