H2-003
Product Specifications
UNSPSC Description
H2-003 is a selective human DGAT2 inhibitor that inhibits triglyceride (TG) biosynthesis. H2-003 also effectively inhibits lipid droplet formation in 3T3-L1 cells. H2-003 can be used for research on DGAT2 and TG-related metabolic diseases[1].
Target Antigen
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/h2-003.html
Purity
99.53
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=C(NC(C2=CC=CC=C2)=O)C3=CC(NC(C)CC)=CN=C3N1CC4=CC=CO4)OC
Molecular Weight
446.50
References & Citations
[1]Kim MO, et al. Discovery of a novel class of diacylglycerol acyltransferase 2 inhibitors with a 1H-pyrrolo[2,3-b]pyridine core. Biol Pharm Bull. 2014;37(10):1655-60.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-23199/H2-003-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-23199/H2-003-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1060438-30-3
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal SDHD Antibody [DyLight 755]](https://cdn.genprice.uk/genprice/genprice4.png)
MBS1032511-05 0.02 mg (Baculovirus)
Recombinant Neisseria gonorrhoeae Enolase (eno)
Ask
View Details