H2-003
H2-003 is a selective human DGAT2 inhibitor that inhibits triglyceride (TG) biosynthesis. H2-003 also effectively inhibits lipid droplet formation in 3T3-L1 cells. H2-003 can be used for research on DGAT2 and TG-related metabolic diseases[1].
Product Specifications
CAS Number
[1060438-30-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/h2-003.html
Purity
99.53
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=C(NC(C2=CC=CC=C2)=O)C3=CC(NC(C)CC)=CN=C3N1CC4=CC=CO4)OC
Molecular Formula
C25H26N4O4
Molecular Weight
446.50
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-23199/H2-003-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-23199/H2-003-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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