(Benzotriazol-1-yloxy) tripyrrolidinophosphonium (hexafluorophosphate)

(Benzotriazol-1-yloxy) tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and BOP analog. (Benzotriazol-1-yloxy) tripyrrolidinophosphonium hexafluorophosphate promotes the reaction of amino and carboxyl groups to form peptide bonds. (Benzotriazol-1-yloxy) tripyrrolidinophosphonium hexafluorophosphate can be used in the synthesis of peptide compounds[1][2]

Product Specifications

CAS Number

[128625-52-5]

Product Name Alternative

Benzotriazole-1-yl-oxytripyrrolidinophosphonium (hexafluorophosphate)

UNSPSC

12352200

Hazard Statement

H302, H317, H410

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/benzotriazol-1-yloxy-tripyrrolidinophosphonium-hexafluorophosphate.html

Purity

99.90

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

F[P-](F)(F)(F)(F)F.C12=CC=CC=C1N=NN2O[P+](N3CCCC3)(N4CCCC4)N5CCCC5

Molecular Formula

C18H28F6N6OP2

Molecular Weight

520.39

Precautions

H302, H317, H410

References & Citations

[1]Coste J, et al., PyBOP®: A new peptide coupling reagent devoid of toxic by-product[J]. Tetrahedron Letters, 1990, 31 (2) : 205-208.|[2]Frérot E, et al. PyBOP® and PyBroP: Two reagents for the difficult coupling of the α, α-dialkyl amino acid, Aib. Tetrahedron, 1991, 47 (2) : 259-270.