CRA1000
CRA1000 is an orally active, selective and competitive CRF1 receptor antagonist with anxiolytic- and antidepressant-like properties[1].
Product Specifications
CAS Number
[226948-11-4]
UNSPSC
12352005
Target
CRFR
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cra1000.html
Smiles
FC1=CC=CC(C2=CCN(CC2)C3=NC(N(CC)C4=CC=C(C(C)C)C=C4SC)=NC(C)=C3)=C1
Molecular Formula
C28H33FN4S
Molecular Weight
476.65
References & Citations
[1]Okuyama S, et al. Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001. J Pharmacol Exp Ther. 1999 May;289 (2) :926-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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